This page features combatants who happen to be siblings.
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A
- Akame
- Akane Owari
- Aki Hayakawa
- Akira Kazama
- Akuma
- Akuma Shogun
- Amanda Waller
- Anais Watterson
- Android 17
- Android 18
- Anne Boonchuy
- Ant-Man (Scott Lang)
- Anti-Monitor
- Applejack
- Aquaman
- Ares (DC Comics)
- Ares (God of War)
- Ares (Marvel Comics)
- Ariel
- Arvis
- Asta
- Ataru Kinniku
- Atom (DC Comics)
- Azrael (DC Comics)
B
C
D
K
L
M
P
S
- Sakura Kasugano
- Sam Winchester
- Sanemi Shinazugawa
- Sans
- Sasuke Uchiha
- Satori Komeiji
- Satsuki Kiryuin
- Savage Opress
- Scarlet King
- SCP-076
- Shelob
- Sheriff (Mutant Busters)
- Shinobu Kocho
- Shion Sonozaki
- Shoto Todoroki
- Sideswipe
- Snow Miser
- Sokka
- Solidus Snake
- Sprig Plantar
- Squid Sisters
- Stanford Pines
- Stanley Pines
- Stocking Anarchy
- Strider Hiryu
- Suigintou
- Surly
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