Essentially the main character that a story follows. There can be more than one main protagonist in a story but traditionally it's one. Note that main characters are the same as main protagonists and main antagonists.
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A
- Aang
- Abe (Oddworld)
- Abobo (Abobo's Big Adventure)
- Abraham Lincoln (Vampire Hunter)
- Accelerator
- Adam Jensen
- Aelita Schaeffer
- Aeon Flux
- Aera Colthearts
- Aerrow
- Aether
- Afro Samurai
- Agent 47
- Agent J
- Agumon
- Aiai
- Aiden Pearce
- Aigis
- Ainz Ooal Gown
- Akane Owari
- Akira Yuki
- Aladar
- Aladdin (Disney)
- Alear (Fire Emblem)
- Alex DeLarge
- Alex Kidd
- Alex Mercer
- Alex Russo
- Alex the Lion
- Alibaba Saluja
- Alice Liddell
- Alien Hominid
- Alita
- Allen Walker
- Alucard (Hellsing)
- Alucard (Mobile Legends)
- Amaterasu
- Ambush Bug
- Anakin Skywalker
- Anakin Skywalker VS Sunset Shimmer
- Andy (Heart of Darkness)
- Ann Takamaki
- Anne Boonchuy
- Anos Voldigoad
- Ant-Man (Scott Lang)
- Aqua (Kingdom Hearts)
- Aqua (Kono Subarashii Sekai ni Shukufuku Wo!)
- Aquaman
- Aragorn
- Arale Norimaki
- Arata Kasuga
- Arcueid Brunestud
- Ariel
- Arle Nadja
- Artemis Fowl
- Arthur (Ghosts 'n Goblins)
- Arthur Morgan
- Asagi
- Asami Sato
- Ash Crimson
- Ash Ketchum
- Ash Williams
- Ash Williams vs. Hellboy
- Ashitaka
- Asta
- Asterix
- Astro Boy
- Asuka (Senran Kagura)
- Asura
- Asura (Samurai Shodown)
- Atom (DC Comics)
- Atom (Real Steel)
- Atomic Betty
- Atsuko Kagari
- Aurora (Child of Light)
- Austin Powers
- Axe Cop
- Axel Stone
- Aya Brea
- Aya Drevis
- Ayaka Kagari
- Azrael (DC Comics)
B
- Baby (Baby Driver)
- Baki Hanma
- Bane
- Banjo & Kazooie
- Baoh (Ikuro Hashizawa)
- Barbie
- Barnabas Collins
- Baron Helmut Zemo
- Bart Simpson
- Batgirl
- Batman
- Batman Beyond
- Bayonetta
- Beast Boy
- Beat
- Beatrice
- Beatrix LeBeau
- Beck
- Bell Cranel
- Ben Tennyson
- Ben Tennyson vs Aang
- Beta Ray Bill
- Big the Cat
- Bill & Ted
- Bill Overbeck
- Bill Rizer
- Black General
- Black Hat
- BlackGuy
- Blade (Gunvolt Chronicles)
- Blade (Puppet Master)
- Blake Belladonna
- Blinx
- Blitzo
- Bloody Bunny
- Bloom
- Blossom
- Blue (Pokémon)
- Blue Mary
- Bobobo-bo Bo-bobo
- Bodi (Rock Dog)
- Bomberman
- Boog
- Boruto Uzumaki
- Bowser Junior (SML)
- Bub (Bubble Bobble)
- Bubbles
- Buck (Jack London)
- Bucky O'Hare
- Buffy Summers
- Bug
- Bugs Bunny
- Bulkhead
- Bumblebee (Transformers)
- User blog:Bunny Cat4/Pop Cat (Let's write a story)
- Burt Gummer
- Buster Bunny
- Buttercup
- Buzz Lightyear
- Byleth
C
- C-Sha
- Cadence
- Caesar (Planet of the Apes)
- Caesar Zeppeli
- Cal Kestis
- Caleb (Blood)
- Calliope Mori
- Camilla
- Cammy White
- Candace Flynn
- Captain Rainbow
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- Carmelita Fox
- Cattleya
- Cerebella
- Charlie Morningstar
- Cheetara
- Chen Jingchou
- Chester Cheetah
- Chikn Nuggit
- Chosen Undead
- Chou-Chou
- Chris Redfield
- Chrom
- Chun-Li
- Claude (GTA)
- Cloud Strife
- Coco Bandicoot
- Cody Travers
- Cole MacGrath
- Conan the Barbarian
- Conker
- Connor (Detroit: Become Human)
- Corrin
- Corvo Attano
- Courage
- Crash Bandicoot
- Cream the Rabbit
- Crimson Bolt
- Crybaby
- Crypto
- Cuphead
- Cyborg 009 (Joe Shimamura)
- Cynder (Spyro)