User blog comment:Pikazilla/How to Kill One Punch Man/@comment-31768882-20170913153036

Axel (Disgaea) with the A-Virus, Ambush

Axel could infect Saitama with the A-Virus just by being near him (That's how the main cast got infected) or by having someone who's already infected be near him. Saitama would be infected and he would turn into Axel both physically and mentally, the person known as Saitama would cease to exist and would become another Axel.

The only known ways to cure the A-Virus are by having or to drink an angel's blood or by having such a strong will that you force the virus out, Saitama has neither (Valvatorez's will could defy God and he was the only one who had a strong enough will).