User blog comment:DoomFest/~ The Great Thumbnail Contest - SEASON 3 ~/@comment-4363364-20160526122233/@comment-26561766-20160526141823

43 -> Take the thing literally.

44 -> You guess the duo.

45 -> Both Dante and Vergil have been done. So it isn't one of the two.

46 -> Yep, there's a Pokemon.

47 ->  That's actually the one in the background image.

48 -> No. But you aren't far.

49 -> There isn't Riku;

50 -> And yes, there's a Naruto character.

Yeah, I know these hints are more obscure. But that's voluntary, so that's why I give answers to your guesses ;)